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Characteristics and Treatment Response of Patients with HIV Associated Kaposi’s Sarcoma in Central Kenya

Posted on June 27, 2025
HIV patient consulting a male doctor in clinic

Abstract
Background
Kaposi’s sarcoma (KS) remains a significant malignancy in HIV-positive populations in sub-Saharan Africa. This study aimed to characterize patients with HIV-associated KS and evaluate their treatment outcomes in central Kenya.

Methods
A retrospective cohort study was conducted using routine program data from HIV care and treatment facilities. Clinical and demographic characteristics, treatment regimens, and follow-up data were analyzed.

Results
Majority of patients were male and under antiretroviral therapy (ART) before KS diagnosis. Most presented with advanced KS, and treatment included chemotherapy alongside ART. However, delays in chemotherapy initiation and loss to follow-up were prevalent.

Conclusion
Improving early KS diagnosis and timely chemotherapy, integrated with ART services, is critical to better outcomes in HIV-associated KS management in Kenya.

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