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Feasibility of Smartphone-Enabled Asynchronous Video Directly Observed Therapy Among HIV Unsuppressed Children and Adolescents in Kenya

Posted on June 27, 2025
Teenage girl using mobile phone under blanket

Abstract
Background
Poor ART adherence contributes to viral non-suppression in children and adolescents. This study assessed the feasibility of video directly observed therapy (VDOT) using smartphones.

Methods
Participants were unsuppressed HIV-positive children and adolescents aged 10–19 years. They used smartphones to record daily ART ingestion videos, reviewed asynchronously by healthcare workers.

Results
VDOT was feasible and acceptable. Over 80% adherence was recorded among participants, and significant improvement in viral suppression was noted at 3-month follow-up.

Conclusion
Asynchronous smartphone-enabled VDOT is a promising approach to enhance adherence and viral suppression in youth living with HIV.

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